Top 10 pharmacies in Sioux Falls
Ranked by how complete and owner-verified the listing info is — hours, phone, website, services. No pay-to-play.
-
1Lewis Pharmacy
2700 W 12th St, Sioux Falls, SD 57104
-
2Caretrends Pharmacy
6709 S Minnesota Ave Ste 105, Sioux Falls, SD 57108
-
3CVS Pharmacy
1021 S Highline Pl, Sioux Falls, SD 57110
BEFORE YOU GO
Plan your next pharmacy visit
Organize refills, transfers and prescription pickup with the pharmacy.

Plan a refill
Submit a refill request to the right pharmacy, distinguish authorization from insurance processing, and leave each follow-up with a named next step.
Read the guide
Arrange a transfer
Ask the receiving pharmacy to check eligibility, coordinate the record transfer and confirm the new pickup arrangement without assuming every prescription can move.
Read the guide
Confirm pickup timing
Get the exact collection deadline from your pharmacy, clarify what its status message means and ask what happens if you cannot arrive in time.
Read the guide-
4Pharmacy Specialties and Clinic Inc.
2333 W 57th St, Sioux Falls, SD 57108
-
5Sanford Hematology and Oncology Pharmacy
1309 W 17th St St 101, Sioux Falls, SD 57104
-
6Hy-Vee Pharmacy
4101 South Louise Avenue, Sioux Falls, SD 57106
-
7Sioux Falls Surgical Center Pharmacy
910 E 20th St, Sioux Falls, SD 57105-1012
-
8Sam's Club Pharmacy
3201 S Louise Ave, Sioux Falls, SD 57106-0704
-
9Avera Pharmacy - 7th Ave
1200 S 7th Ave, Sioux Falls, SD 57105
-
10PharMerica – Sioux Falls, SD
1507 W 51st St, Sioux Falls, SD 57105
Of the 23 pharmacies listed in Sioux Falls, 23 give a phone number and 21 have a website.
All 13 other pharmacies in Sioux Falls
By ZIP code: 57103 (4) · 57105 (3) · 57106 (2) · 57108 (3) · 57110 (1)
ZIP 57103 4
-
Lewis Drug
1301 E 10th St, Sioux Falls, SD 57103-1780
-
Hy-Vee Pharmacy
3020 East 10th Street, Sioux Falls, SD 57103
-
True Care Family Pharmacy
1120 E 10th St, Sioux Falls, SD 57103
-
Lewis Drug
E. 26th St., Sioux Falls, SD 57103
ZIP 57105 3
-
Hy-Vee Pharmacy
3000 South Minnesota Avenue, Sioux Falls, SD 57105
-
Avera Doctors Plaza 2 Pharmacy
1100 E 21st St, Sioux Falls, SD 57105-1000
-
Sanford Medical Center Pharmacy
1305 W 18th St, Sioux Falls, SD 57105
ZIP 57106 2
-
Cvs Pharmacy
3600 S Louise Ave, Sioux Falls, SD 57106-6326
-
Lewis Drug
5500 W 41st St, Sioux Falls, SD 57106
ZIP 57108 3
-
Lewis Drug
6109 S Louise Ave, Sioux Falls, SD 57108
-
Hy-Vee Pharmacy
1231 East 57th Street, Sioux Falls, SD 57108
-
Avera Pharmacy - S Minnesota Ave
6701 S Minnesota Ave, Sioux Falls, SD 57108
ZIP 57110 1
-
Hy-Vee Pharmacy
1601 South Sycamore Avenue, Sioux Falls, SD 57110