The 10 Best Pharmacies in South Carolina — 2026

We compared all 764 pharmacies in South Carolina on the data that matters: services offered, posted hours, and how easy each one is to reach. No pay-to-play — this ranking comes straight from the listings data, updated November 2026.

#1 · CVS PharmacyRock Hill

(803) 366-4157 Website View listing

#2 · Dottie's PharmacyCharleston

(843) 501-9500 Website View listing

#3 · Hawthorne Camden PharmacyCamden

(803) 425-8378 Website View listing

#4 · Mobley DrugsLancaster

(803) 285-2021 Website View listing

#5 · Union Family PharmacyUnion

(864) 427-3700 Website View listing

#6 · Bluffton PharmacyBluffton

(843) 757-4999 Website View listing

#7 · The PharmacyFlorence

(843) 773-2821 Website View listing

#8 · Hibbitts Drug Co.New Ellenton

(803) 443-0077 Website View listing

#9 · Reidville Road PharmacySpartanburg

(864) 435-9400 Website View listing

#10 · Elgin PharmacyElgin

(803) 438-5735 Website View listing

Run one of these businesses? You earned this spot — email contact@pharmacyatlas.com for your free “Top Pharmacies in South Carolina” badge to put on your site, and we’ll make sure your listing stays accurate.
How we rank: every listing earns points for listed services (compounding, specialty pharmacy), posted hours, and working contact details. The ranking is recalculated with every data update.